From VCF to report.
In minutes, not days.
Review evidence, classify variants, and generate structured reports in one environment.
Complete answers. For every patient. Every time.
Spend less time on routine, and more time on the work only you can do. Vgen23 frees you from tools management so you can provide answers for every patient, knowing that everything is fully secure with international standards.
The bottleneck starts after sequencing.
Generating data is no longer the hardest part. Interpretation, review, and reporting still happen across fragmented tools, manual checks, and report templates that slow your team down.
Too many tabs
ClinVar, gnomAD, OMIM, PubMed, IGV, spreadsheets, internal notes. Critical evidence is spread across tools that were never built to work together.
ACMG review still stays manual
Automated scoring helps, but someone still has to verify criteria, inspect the evidence, and make sure every call is traceable.
VUS work does not stay organized
Variants of uncertain significance accumulate quickly, but most workflows do not give teams a structured way to review, revisit, and respond over time.
Reports still get assembled by hand
Patient details, evidence references, OMIM links, and report formatting are often stitched together manually when they should already be part of the workflow.
One environment. Everything in front of you.
Vgen23 brings your entire interpretation workflow into a single workspace. Stop switching tabs.
Start reviewing variants.
Every database. One view.
Each variant annotated against 100+ databases - ClinVar, gnomAD, OMIM, PubMed, Indian Genome AF, and more. Population frequency, functional predictions, conservation scores - all traceable to source.
Classification with a visible evidence trail.
Apply ACMG/AMP criteria with a visible evidence trail. Review triggered criteria, inspect supporting evidence, and keep every change audit-logged.
See how variants, genes, diseases, and phenotypes connect.
A network visualization of relationships across your case. Spot convergent evidence. Identify shared phenotypes across candidate genes. Prioritize visually instead of scanning rows.
Describe symptoms in your own words. In any language.
Type clinical text as it appears in a referral note. The platform maps it to standardized HPO terms - in English, Hindi, Tamil, or other native scripts. No manual HPO lookup.
Genome visualization without switching tools.
Integrated IGV browser for every variant. Confirm read alignment and sequencing quality without leaving the analysis.
Reports that match your format. Generated, not assembled.
Select variants, add to report, download as PDF. Case information, evidence references, and OMIM IDs populate automatically. Your template. Your branding. Consistent every time.
Built for the workflows labs run today.
Germline Proband
Phenotype-to-genotype and genotype-to-phenotype review in one workflow.
Germline Trios
Family-based review with de novo and segregation support.
Targeted Panels
Structured interpretation for disease-specific panels.
Somatic
Interpretation support for somatic workflows with tumor-focused reporting.
Built for the populations you see everyday.
Global reference databases still underrepresent South Asian populations. Vgen23 integrates Indian Genome allele frequency data alongside widely used global databases so interpretation decisions reflect the population your lab actually serves.
Validated across germline, somatic, and ranking workflows.
Performance claims are specific, reviewable, and tied to real evaluation cohorts.
Germline WES validation
100-patient cohort. 130 evaluated sites. 99.1% sensitivity. 100% specificity. Vgen23 detected 112 of 113 true positive variants with no false positives.
Somatic validation
96 lung cancer patients. 119,022 somatic variants evaluated. 99.6% sensitivity.
Phenotype-to-genotype ranking
39 individuals with affected and unaffected controls. 93.1% sensitivity. 100% specificity. Affected variants ranked in the top 1 to 5.
Genotype-to-phenotype ranking
Most detected variants ranked in the top 1 to 20, with 63% in the top 1 to 5.
Security and compliance built for your workflows.
Vgen23 runs with documented security controls, auditability, and a full trust package available through our Trust Center.
Simple self-serve pricing
Create an account, upload a VCF, and evaluate Vgen23 on your own cases.
No sales call required.
WES from 2,500 credits | 3,000 free credits to start
See Full Pricing →Built by the team at Vgenomics
Vgen23 is built by the internationally recognized team at Vgenomics, a biotech company built by scientists from India and the US, accelerating discoveries for genetic diseases.
Learn more about the company behind Vgen23
About VgenomicsTry it on your own case.
Upload your own case to see how Vgen23 ranks and structures the review,
and evaluate it on your current workflow.
Free Trial. All Premium Features. 3,000 credits.
2 minutes to create an account. Instant access.